Fualaau vaega, lea e faaaoga e le faiga o le vailaau

Fualaau o oloa o microorganisms, manu ma laau, faapea foi ma o latou mafuaaga e gaosia ma semisynthetic o le oloa o lenei laina, lea i le tino o le tagata po o se manu faaleagaina pe taofia lē tumau le atinae o faatupu faamai mai fafo. Fualaau e aafia ai foi le fua faatatau o le tali biochemical. I le taimi nei, tatou te synthesized e se eseese o fualaau, ae na o nisi oi latou o loo faaaogaina i faiga faafomai. ua tatau ona totogi lenei ia latou toxicity maualuga. O le vaega autu o le fualaau o loo maua mai i meaola, aano o le tino o manu ma laau.

O mea o loo mata autu mo le tuuina vailāʻau e fungi (griseofulvin, penisilini), actinomycetes (tetracyclines, rifamycins, streptomycin, chloramphenicol, cephalosporins, aminoglycosides, polyenes), fungi (fuzidin-), siama (gramicidin, polymyxin), lichen (acid usnic), Laau (rafanin, imanin, volatile), manu (lysozyme, erythrite, Leikin, o se interferon, ekmolin, gamma globulins).

fualaau Antifungal - biosoedineny vaega eseese e mafai ona faaumatia membranes moni o fungi microscopic, na mafua ai lo latou oti. O loo sili ona lauiloa e pei o fualaau faasaina o le "Levorinum", "Natamycin" "Nystatin". I aso nei, e le masani ona faatonuina nei fualaau faasaina, ona o le maualalo o le lelei ma toxicity maualuga. faletalavai po nei ofoina atu se vaega tele o matua lelei fungicides gaosi, ua suia malie le fualaau antifungal.

Mafaufau i le faatulagaga vailaau iloa e pei o vaega o fualaau: cephalosporins, penicillins, macrolides, levomitsitin, tetracyclines, polymyxins, aminoglycosides, rifamycins ma polyenes. Fualaau, e le pei antiseptics vailaau, pau i luga o le laualuga o se feaveai microbial pe ati i totonu, e oo lava i tamai concentrations osmotic solia ana galuega tauave taua (o ni kopi, manava, meaai) faaalia bactericidal ma gaoioiga bacteriostatic.

faiga vailāʻau o Groups gaoioiga: inhibitors membrane feaveai (cephalosporins, penicillins); inhibitors o vaega eseese o le biosynthesis o polotini ma acids nucleic (levomitsetina, streptomycins, aminoglycosides, tetracyclines, macrolides, rifamycins, hloromitsiny, actinomycins). O fualaau faasaina e sili ona matautia mai lenei vaega o fualaau levomitsetina ma aminoglycoside lea e mafai ona mafua leiloa o le su ivi, ate ma fatugaʻo.

Faafetai i le tekinolosi i aso nei ua uma ona suesue i le faiga o le gaoioiga antimicrobial o fualaau i le tulaga molecular, lea e faalauteleina ai le malamalama o le faiga faavae o loo tutupu i lalo o latou aafiaga. Mo se faataitaiga, o tagata suesue o loo maua e faapea o le solia o porotini teratsiklina tuufaatasia i lalo o le aafiaga o fualaau oona, chloramphenicol ma erythromycin tutupu i vaega eseese. Levomitsetina taofiofia le gaoioiga o le transferase peptidyl enzyme, erythromycin galue i luga o le enzyme translocase, ma tetracyclines - le faagasologa o le faapipiiina o le faaliliuina acid ribonucleic i le ribosome.

fualaau vaega, na tuuina mai le tele o gaoioiga antimicrobial. ua faavasegaina uma fualaau pei o fualaau faasaina o le vaapiapi ma le lautele o fusi o alaleo o gaoioiga. O formulations fusi o alaleo o le vaapiapi o le "erythromycin", "oleandomycin" - galue preferentially i microflora polokalama-lelei ma polymyxin - i polokalama ma polyenes - mo fungi.

O le sauniuniga ma le lautele o fusi o alaleo o le faatinoga (streptomycins, levomitsitin, tetracyclines, aminoglycosides) galue o i polokalama-lelei ma polokalama-lelei microflora, faapea foi ma nisi siama, fungi, rickettsia, leptospira, protozoa.